Why Can’t Medical Study Results on Men Apply to Women as Well?

Question by eediuts_lurking: Why can’t medical study results on men apply to women as well?
For example, I just read this morning the following: “New guidelines from the American Heart Association – It is the first time guidelines have urged all women to consider aspirin for preventing strokes…”

A ton of research seems to center on men initially. Men and women’s bodies differ in some ways, but when studies focusing on treatments for diseases of the heart, kidneys, blood, etc., (something all humans have), why shouldn’t the results for the new standards of treatment apply to both men AND women?

Best answer:

Answer by Catana
Diseases don’t necessarily express themselves in the same way in men and women. Women have different symptoms of heart disease than men do. They also may react differently to drugs used for treatment.

Answer by Orinoco_W
Women and men have different bodies, different hormones and they have different rates of stroke and heart disease before menopause.

In women, the menstrual cycle seems somewhat protective of the vascular system. It turns out that if you give aspirin to people who are less likely to have heart attacks or strokes, then you actually wind up subjecting them to the risks (of bleeding, bruising, and rarely haemorrhagic bleeds in the brain etc) without much of the benefit of cardioprotection/stroke protection.

This is why studies on men are not always applicable to women.

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